Diabetes occurs due to damage to cells that produce insulin in the pancreas, so that the body loses its ability to regulate blood sugar levels.
Professor Ian G Gallicanp daro Georgetown University Medical Center, Washington DC, change the initial precursor for human sperm, known as spermatogonial stem cells (SSCs), a beta-islet cells.
Islet beta cells have the ability to produce insulin, which is generally produced in the pancreas. When injected into mice, these cells successfully regulate blood sugar levels in the body of the mice.
As quoted from page Guardian, Gallicanp his team presented the results of experiments at the annual meeting of the 'American Society for Cell Biology' in Philadelphia.
"Without stem cells, adult or embryonic forced to produce sufficient insulin to cure diabetes in humans. But, but we know that SSCs have the potential to do what we want, and we know how to develop it," said Gallicano.
Gallicanp and his team perform extraction of human SSCs from the testicles of the dead. "From the testicles, these cells will form three germ layers in a few weeks and will develop into tissue in the body," he said.
Of the approximately one gram of testicular tissue from humans, researchers produce about one million stem cells. These cells showed the content of biological marker that is identical to beta-islet cells, producing insulin.
Tues that then transplanted into the body of mice. This has been engineered mice have no immune system so that blood levels decreased. After obtaining the cell grafts for a week, the rat began to have the ability to produce insulin to regulate blood sugar levels.
Researchers continue to develop its findings. They experimented for humans, at least in men with type 1 diabetes, may use its own testicular tissue to produce insulin replacement. They are also being tested the ability of stem cells in the female egg cell.
